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Superparamagnetic Copper Ferrite Nanoparticles Catalyzed One Step Regioselective Synthesis of Dibenzodiazepinones via Ligand and Base Free Ullmann Type Coupling Reaction
Author(s) -
Jamatia Ramen,
Gupta Ajay,
Pal Amarta Kumar
Publication year - 2016
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201500038
Subject(s) - catalysis , regioselectivity , superparamagnetism , coupling reaction , nanoparticle , copper , materials science , thermal stability , combinatorial chemistry , ferrite (magnet) , x ray photoelectron spectroscopy , ligand (biochemistry) , chemical engineering , chemistry , organic chemistry , nanotechnology , magnetization , metallurgy , physics , quantum mechanics , magnetic field , engineering , biochemistry , receptor , composite material
CuFe 2 O 4 superparamagnetic nanoparticles were used as an efficient heterogeneous catalyst for the one‐step synthesis of dibenzodiazepinones via Ullmann type coupling reaction. The catalyst was highly stable, efficient and easily synthesized from readily available starting materials. The prepared CuFe 2 O 4 NPs was characterized using various characterization techniques such as TEM, SEM, EDX, XRD, VSM, XPS and FT‐IR analysis. The thermal stability of the catalyst was also examined by TGA analysis. The present methodology eliminates the multistep procedure for the synthesis of the said compounds. The catalyst efficiently catalyzed the reaction under milder condition furnishing high yield of the product within a short reaction time with higher regioselectivity. Furthermore, the CuFe 2 O 4 super paramagnetic nanoparticles could be easily separated by an external magnet and reused for four consecutive runs. The present protocol is devoid of any base or ligands and showed excellent result for reproducibility and gram scale reaction which addressing the issues of sustainability and environment friendliness.