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Bayesian analysis of recurrent event with dependent termination: an application to a heart transplant study
Author(s) -
Ouyang Bichun,
Sinha Debajyoti,
Slate Elizabeth H.,
Van Bakel Adrian B.
Publication year - 2012
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.5717
Subject(s) - bayesian probability , prior probability , event (particle physics) , heart transplantation , computer science , medicine , covariate , intensive care medicine , transplantation , machine learning , artificial intelligence , physics , quantum mechanics
For a heart transplant patient, the risk of graft rejection and risk of death are likely to be associated. Two fully specified Bayesian models for recurrent events with dependent termination are applied to investigate the potential relationships between these two types of risk as well as association with risk factors. We particularly focus on the choice of priors, selection of the appropriate prediction model, and prediction methods for these two types of risk for an individual patient. Our prediction tools can be easily implemented and helpful to physicians for setting heart transplant patients' biopsy schedule. Copyright © 2012 John Wiley & Sons, Ltd.