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Use of the gibbs sampler to estimate transition rates between grades of coronary disease following cardiac transplantation
Author(s) -
Sharples Linda D.
Publication year - 1993
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4780121205
Subject(s) - gibbs sampling , medicine , transplantation , cardiology , coronary artery disease , mathematics , statistics , bayesian probability
Abstract Coronary occlusive disease following cardiac transplantation is monitored using serial angiography, and graded on a 3 point scale according to the amount of narrowing observed in major vessels. Disease progression is modelled as a continuous time Markov process. The Gibbs sampler is used to estimate the marginal posterior distributions of the transition rates between grades of disease and from each grade to death.