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Issues in analysing the effects of occupational exposure to low levels of radiation
Author(s) -
Gilbert E. S.
Publication year - 1989
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4780080205
Subject(s) - comparability , extrapolation , confidence interval , environmental health , radiation exposure , statistics , econometrics , environmental science , computer science , risk analysis (engineering) , medicine , mathematics , combinatorics , nuclear medicine
A major objective of studying populations exposed to low levels of radiation is provision of direct assessment of the adequacy of estimates of health risks obtained by extrapolation of data on populations exposed at high levels. Meeting this objective requires the use of statistical methods that fully utilize available exposure measurements, and that consider the extensive body of prior knowledge regarding radiation‐induced health effects. This paper describes various methods of analysis and illustrates the methods with data on workers at the Hanford Site. Special problems are discussed, with attention to comparability of estimates and confidence limits with those obtained from extrapolation.