Modelling binary data from a three‐period cross‐over trial | Zendy

Jones Byron | Zendy; Kenward Michael G. | Zendy

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Modelling binary data from a three‐period cross‐over trial

Author(s) -

Jones Byron,

Kenward Michael G.

Publication year - 1987

Publication title -

statistics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.996

H-Index - 183

eISSN - 1097-0258

pISSN - 0277-6715

DOI - 10.1002/sim.4780060504

Subject(s) - binary data , crossover study , binary number , cross over , period (music) , crossover , statistics , placebo , extension (predicate logic) , computer science , mathematics , medicine , artificial intelligence , arithmetic , alternative medicine , physics , pathology , acoustics , programming language

A new method of analysing binary data from a three‐treatment, three‐period cross‐over trial is described. This method is based on a log‐linear model and mirrors the analysis of continuous data. It is an extension of the method we introduced recently for the analysis of binary data from a two‐treatment, two‐period crossover trial. We illustrate our method using data from a trial which compared two analgesics and a placebo for the relief of primary dysmenorrhea.

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