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Allocation designs in cohort and case‐control studies
Author(s) -
Moussa Mohamed A. A.
Publication year - 1986
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4780050404
Subject(s) - flexibility (engineering) , computer science , control (management) , optimal design , risk analysis (engineering) , resource allocation , power (physics) , operations research , operations management , reliability engineering , econometrics , medicine , statistics , economics , mathematics , engineering , machine learning , artificial intelligence , computer network , physics , quantum mechanics
Four unequal allocation designs for cohort and case‐control studies that incorporate cost and power are considered and compared with the equal allocation design, with the aim of providing researchers some flexibility in planning their studies. It is found that the type of design to be adopted depends on available resources and projected needs. In the case of tight expenditure, the minimized cost design is the optimal, whereas the maximized power design may be sought if the researcher intends to ensure a high chance of detecting any clinically significant relative risk of disease.