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Approaches to sample size estimation in the design of clinical trials—a review
Author(s) -
Donner Allan
Publication year - 1984
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4780030302
Subject(s) - sample size determination , estimation , computer science , clinical trial , sample (material) , research design , clinical study design , medical physics , econometrics , statistics , medicine , mathematics , engineering , systems engineering , chemistry , pathology , chromatography
Over the last decade, considerable interest has focused on sample size estimation in the design of clinical trials. The resulting literature is scattered over many textbooks and journals. This paper presents these methods in a single review and comments on their application in practice.