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Clinical trials: Some reflections
Author(s) -
Holland Walter W.,
Breeze Ellie,
Swan Anthony V.
Publication year - 1982
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4780010414
Subject(s) - clinical trial , medical physics , computer science , management science , epistemology , medicine , philosophy , engineering , pathology
The principles and historical development of clinical trials are outlined briefly. Some issues that extend the basic philosophy first put forward by Sir Austin Bradford Hill 40 years ago and that will need consideration in the future application of clinical trials are discussed.