z-logo
Premium
A new classification approach for comparing two active treatments when there is no prior projection on which one is better
Author(s) -
Qu Yongming,
Liu Rong,
Dmitrienko Alexei,
Offen Walter
Publication year - 2011
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.4402
Subject(s) - projection (relational algebra) , computer science , artificial intelligence , statistics , mathematics , algorithm
We developed a new classification approach in this paper to compare two active treatments. This approach is especially useful when there is no prior judgment on which treatment is better and the traditional hypothesis testing approach is thus not applicable. Our method classifies all the possible outcomes into categories and draws conclusions on the difference in the outcome measurement between two treatment arms according to the location of the confidence interval for the treatment difference in the response variable. This method controls the misclassification rate regardless of the true difference in the response between the two treatment arms. The method was applied to a diabetes clinical trial. Copyright © 2011 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here