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Comparing methods of measurement: Extending the LoA by regression
Author(s) -
Carstensen Bendix
Publication year - 2009
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.3769
Subject(s) - regression , statistics , range (aeronautics) , regression analysis , construct (python library) , simple (philosophy) , loa loa , mathematics , computer science , observational error , simple linear regression , linear regression , meaning (existential) , econometrics , psychology , zoology , philosophy , epistemology , biology , programming language , materials science , composite material , psychotherapist , helminths , filariasis
Method comparison studies are usually analyzed by computing limits of agreement (LoA). If only one measurement by each method is taken on each person, and the difference across the range is not constant, it has been suggested ( Stat. Methods Med. Res. 1999; 8 :136–160) to regress the differences on the averages and use the resulting equation to construct LoA. LoA can be converted to a prediction foumula for one method given a measurement by the other. The meaning of the regression of differences on means is clarified in the framework of a proper model and prediction equations linking one method to another are devised. The performance of this model based method is evaluated against the simple approach proposed earlier and against the Deming regression. Copyright © 2009 John Wiley & Sons, Ltd.