Premium
Semiparametric ROC surfaces for continuous diagnostic tests based on two test measurements
Author(s) -
Wan Shuwen,
Zhang Biao
Publication year - 2009
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.3625
Subject(s) - nonparametric statistics , parametric statistics , estimator , semiparametric model , semiparametric regression , parametric model , computer science , receiver operating characteristic , statistics , econometrics , mathematics
We propose a semiparametric method for estimating ROC surfaces for continuous diagnostic tests based on two test measurements. Such a three‐class diagnostic problem based on two test measurements arises naturally from some DNA amplification‐related diagnostic scenarios. Simulation results show that our proposed semiparametric ROC surface estimator is more efficient than the nonparametric counterpart and is quite comparable with the parametric counterpart when model assumption of the data is correctly specified for the parametric method. Moreover, when the parametric model assumption is not true, our proposed semiparametric method is superior to both nonparametric and parametric methods. Some discussions and a simulated example along with R programs for implementation of the proposed method are also provided. Copyright © 2009 John Wiley & Sons, Ltd.