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An introductory note to CHMP guidelines: choice of the non‐inferiority margin and data monitoring committees
Author(s) -
Brown David,
Volkers Peter,
Day Simon
Publication year - 2006
Publication title -
statistics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.996
H-Index - 183
eISSN - 1097-0258
pISSN - 0277-6715
DOI - 10.1002/sim.2561
Subject(s) - margin (machine learning) , computer science , machine learning
The Committee on Medical Products for Human Use (CHMP) has recently issued two new guidance documents that are of particular note to statisticians. The purpose of this short note is to give a little background to the origins of these documents and a flavour of some of their most important features. The two guidelines are reproduced as the next two papers in the journal ( Stat. Med. 2006; 25 :1628–1645). Copyright © 2006 John Wiley & Sons, Ltd.