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Nano‐bio interface study between Fe content TiO 2 nanoparticles and adenosine triphosphate biomolecules
Author(s) -
Barkhade Tejal,
Phatangare Ambadas,
Dahiwale Shailendra,
Mahapatra Santosh Kumar,
Banerjee Indrani
Publication year - 2019
Publication title -
surface and interface analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.52
H-Index - 90
eISSN - 1096-9918
pISSN - 0142-2421
DOI - 10.1002/sia.6663
Subject(s) - biomolecule , raman spectroscopy , nanoparticle , anatase , chemical engineering , rutile , chemistry , materials science , nanotechnology , organic chemistry , catalysis , physics , engineering , photocatalysis , optics
The advent of nano‐biotechnology has inspired the interface interaction study between engineered nanoparticles (NPs) and biomolecules. The interaction between Fe content titanium dioxide (TiO 2 ) NPs and adenosine triphosphate (ATP) biomolecules has been envisioned. The effect of Fe content in TiO 2 matrix was studied using X‐ray diffraction (XRD) and transmission electron microscopy (TEM). The increase in Fe content caused a decrease in particle size with change in morphology from spherical to one‐dimensional rod structure. The Fe incorporation in the TiO 2 matrix reduced the transition temperature from anatase to rutile (A‐R) phase along with formation of haematite phase of iron oxide at 400°C. The interaction of Fe content TiO 2 NPs with ATP molecule has been studied using spectroscopic method of Raman scattering and infrared vibration spectrum along with TEM. Fe content in TiO 2 has enhanced the interaction efficiency of the NPs with ATP biomolecules. Raman spectroscopy confirms that the NPs interact strongly with nitrogen (N 7 ) site in the adenine ring of ATP biomolecule. Engineering of Fe content TiO 2 NP could successfully tune the coordination between metal oxide NPs with biomolecules, which could help in designing devices for biomedical applications.

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