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Functional group quantification on epoxy surfaces by chemical derivatization (CD)‐XPS
Author(s) -
Nietzold Carolin,
Dietrich Paul M.,
IvanovPankov Sergej,
Lippitz Andreas,
Gross Thomas,
Weigel Wilfried,
Unger Wolfgang E. S.
Publication year - 2014
Publication title -
surface and interface analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.52
H-Index - 90
eISSN - 1096-9918
pISSN - 0142-2421
DOI - 10.1002/sia.5433
Subject(s) - derivatization , epoxy , chemistry , contact angle , covalent bond , trifluoroacetic anhydride , biomolecule , chemical modification , polymer chemistry , organic chemistry , materials science , composite material , biochemistry , high performance liquid chromatography
In this study, epoxy‐terminated silicon oxide surfaces were chemically derivatized with trifluoroacetic anhydride (TFAA) and 4‐(trifluoromethyl)‐benzylamine (TFMBA) and analyzed by X‐ray photoelectron spectroscopy, near‐edge X‐ray absorption fine structure spectroscopy and water contact angle measurements. TFAA was used for quantitative derivatization to determine the amount of reactive epoxy groups on these surfaces. Furthermore, epoxy‐terminated surfaces were derivatized with TFMBA (a model compound for biomolecules with an amino linker) yielding secondary amines because of formation of covalent C–N bonds between TFMBA and the epoxy films. Fluorine being part of TFAA and TFMBA composition was used to follow the progress of the chemical derivatization reaction. Both derivatization agents – TFAA and TFMBA – gave comparable reaction yields of ~60% on epoxy silicon surfaces, whereas on epoxy glass slides, the derivatization yields were considerably lower (30–40%).The protocol for attachment of TFMBA (model compound) on epoxy‐modified surfaces was adapted to (bio)molecules with an amino linker, e.g. carbohydrates to prepare carbohydrate‐functionalized biointerfaces. Copyright © 2014 John Wiley & Sons, Ltd.