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TOF‐SIMS VG Ionex IX23LS: upgrade and application for the urinary stones analysis
Author(s) -
Ghumman C. A. A.,
Moutinho A. M. C.,
Santos A.,
Tolstogouzov A.,
Teodoro O. M. N. D.
Publication year - 2013
Publication title -
surface and interface analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.52
H-Index - 90
eISSN - 1096-9918
pISSN - 0142-2421
DOI - 10.1002/sia.5031
Subject(s) - calcium oxalate , calcium , chemistry , oxalate , phosphate , analytical chemistry (journal) , inorganic chemistry , chromatography , biochemistry , organic chemistry
TOF‐SIMS VG Ionex IX23LS with upgraded data acquisition and control system was used to study the real urinary stones along with calcium oxalate (COX) and four different calcium phosphate (CP) references. Reliable phase identification of CPs was achieved in the positive SIMS mode on basis of the PO + /POH + and CaPO 2 + /Ca 2 O + peak ratios. In real urinary stones, pure COX was distinguished from calcium phosphates with confidence via the presence of its characteristic ion peaks. We also quantified the calcium phosphate in the human calculi containing calcium oxalate as major or minor component, which is of a great interest for medical community. Copyright © 2012 John Wiley & Sons, Ltd.