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Mesophase‐derived nucleic acid (peptide) self‐organizations visualized by scanning force microscopy
Author(s) -
Meister WalterVeselý,
Bohley Christian,
Lindau Sabine,
Gromann Ulrich,
Naumann Stefan,
Herrmann Bernd,
Kargov Sergej I.,
Martini Torsten,
Barthel Jochen,
Hoffmann Siegfried
Publication year - 2002
Publication title -
surface and interface analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.52
H-Index - 90
eISSN - 1096-9918
pISSN - 0142-2421
DOI - 10.1002/sia.1176
Subject(s) - mesophase , nucleic acid , supramolecular chemistry , scanning force microscopy , peptide , duplex (building) , chemistry , macromolecule , atomic force microscopy , crystallography , dna , nanotechnology , biophysics , materials science , organic chemistry , phase (matter) , biochemistry , biology , crystal structure
For approaching biomesogen self‐organizations in nucleic acid (peptide) assemblies from the perspective of interacting individual macromolecules and their integrating collective mesophase organizations, DNA duplex as well as RNA duplex, triplex, quadruplex and duplex/peptide domains and microdomains have been visualized as graphite surface adlayers by scanning force microscopy. Derived from corresponding mesophase designs, the adlayer imagings of dsDNA, dsRNA and qsRNA reveal aligned supramolecular bundles that follow self‐organizational strategies within the adlayer/interface restrictions. For tsRNA and dsRNA/oligo‐ and polypeptide variations more complex adlayer organizations are observed. Copyright © 2002 John Wiley & Sons, Ltd.