Open AccessFront Cover
Publication year - 2019
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.1002/sctm.12545
Subject(s) - vimentin , retinal , citation , organoid , glioblastoma , induced pluripotent stem cell , stem cell , cover (algebra) , biology , world wide web , computer science , microbiology and biotechnology , genetics , cancer research , embryonic stem cell , immunology , botany , engineering , mechanical engineering , immunohistochemistry , gene
Cover Art: Human induced pluripotent stem cells can be induced to form fully laminated retinal organoids. Methods were defined to isolate retinal Müller glia from these organoids, for potential use in human therapies. The left image shows a laminated retinal organoid labeled for the Müller glial markers vimentin (green) and nestin (red), and the right image shows Müller cells dissociated from these organoids in culture, stained for vimentin (green) and CD29 (red). See Eastlake et al. beginning on page 775 .