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Human anelloviruses and the central nervous system
Author(s) -
Maggi Fabrizio,
Bendinelli Mauro
Publication year - 2010
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/rmv.668
Subject(s) - central nervous system , biology , torque teno virus , pathogenesis , virus , neuroscience , immunology , pathological , virology , medicine , pathology , genetics , genotype , gene
Torque teno virus and related anelloviruses are a recent addition to the list of agents that cause chronic productive infections and high levels of plasma viraemia in humans. Many aspects of the natural history and pathogenesis of these under many respects surprising viruses are still poorly understood. In this review, we briefly outline the general properties of anelloviruses, examine what is currently known about the interactions they establish with the central nervous system (CNS), and discuss the possible pathological consequences. Copyright © 2010 John Wiley & Sons, Ltd.