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Liver involvement in dengue viral infections
Author(s) -
Dissanayake Harsha A.,
Seneviratne Suranjith L.
Publication year - 2018
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/rmv.1971
Subject(s) - dengue fever , viral infection , viral hepatitis , dengue haemorrhagic fever , medicine , virology , pathogenesis , dengue virus , liver injury , immunology , virus
Summary Dengue fever is the commonest viral haemorrhagic fever worldwide and is a leading cause of morbidity and mortality in the tropics. Dengue viral infections are frequently associated with varying degrees of liver injury. Liver injury is more severe in dengue haemorrhagic fever or severe dengue. We review the current knowledge on liver involvement following dengue viral infections and explore the links between clinical manifestations, pathogenesis, and their impact on management