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Hepatitis E: current status
Author(s) -
PérezGracia María Teresa,
Mateos Lindemann María Luísa,
Montalvo Villalba María Caridad
Publication year - 2013
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/rmv.1759
Subject(s) - outbreak , disease , refugee , population , environmental health , medicine , hepatitis a , developing country , hepatitis , developed country , immunology , geography , virology , economic growth , pathology , archaeology , economics
SUMMARY Acute hepatitis E is a very common disease in developing countries, to the point that, according to World Health Organization estimates, one third of the world's population has been exposed to HEV. It also causes outbreaks in refugee camps or after natural disasters such as floods or earthquakes. Sporadic cases of acute hepatitis have been observed in practically all European countries and other developed geographical areas, not only in travelers from endemic countries but also in people with no risk factors. But, lately, new aspects of this infection are appearing in industrialized countries such as the possibility of the disease becoming chronic in transplant patients, the immunocompromised in general, and even in patients with previous liver disease who are immunocompetent. In this comprehensive review, we summarize the current knowledge on HEV infection. Copyright © 2013 John Wiley & Sons, Ltd.