Open AccessLung parenchymal calcifications in a child with cystic fibrosis
Author(s) -
Lynch Heidi,
Qian Frank,
Wong Matthew D.,
Thomas Rahul J.,
Kapur Nitin
Publication year - 2022
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.941
Subject(s) - medicine , pathology , lung , parenchyma , calcification , bronchiectasis , histopathology , fibrosis , cystic fibrosis , biopsy , radiology
We describe a 6‐year‐old girl with homozygous p.Phe508del cystic fibrosis with severe multi‐lobar bronchiectasis and obstructive lung disease who was found to have prominent parenchymal calcifications in the right middle lobe on a computed tomography scan of the chest. Histopathology from the calcified area of lung biopsy showed fibrous tissue with chronic inflammation with CD3+ T‐lymphocytes and macrophages with no granulomas. Dystrophic calcification was seen within this necrotic debris.