Lung parenchymal calcifications in a child with cystic fibrosis | Zendy

Lynch Heidi | Zendy; Qian Frank | Zendy; Wong Matthew D. | Zendy; Thomas Rahul J. | Zendy; Kapur Nitin | Zendy

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Lung parenchymal calcifications in a child with cystic fibrosis

Author(s) -

Lynch Heidi,

Qian Frank,

Wong Matthew D.,

Thomas Rahul J.,

Kapur Nitin

Publication year - 2022

Publication title -

respirology case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.304

H-Index - 9

ISSN - 2051-3380

DOI - 10.1002/rcr2.941

Subject(s) - medicine , pathology , lung , parenchyma , calcification , bronchiectasis , histopathology , fibrosis , cystic fibrosis , biopsy , radiology

We describe a 6‐year‐old girl with homozygous p.Phe508del cystic fibrosis with severe multi‐lobar bronchiectasis and obstructive lung disease who was found to have prominent parenchymal calcifications in the right middle lobe on a computed tomography scan of the chest. Histopathology from the calcified area of lung biopsy showed fibrous tissue with chronic inflammation with CD3+ T‐lymphocytes and macrophages with no granulomas. Dystrophic calcification was seen within this necrotic debris.

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