Open AccessFirst reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus
Author(s) -
Leung Cheuk Cheung Derek,
Chan Yu Hong,
Ho Man Ying,
Chan Ming Chiu,
Chen Chun Hoi,
Kwok Chin Tong,
Yeung Yiu Cheong
Publication year - 2021
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.877
Subject(s) - medicine , mucormycosis , immunosuppression , diabetes mellitus , renal transplant , incidence (geometry) , surgery , amphotericin b , antifungal , dermatology , transplantation , physics , optics , endocrinology
Pulmonary mucormycosis (PM) is a rare, life‐threatening fungal infection usually affecting immunocompromised patients. Its incidence is rising, with a recent outbreak associated with COVID‐19 co‐infection. Amphotericin B along with early surgery are considered the standard treatment. Recurrence has been reported in patients without adequate treatment and without permanent reversal of predisposing factors. We report a case of late recurrence of PM in a renal transplant recipient. In 2012, he was diagnosed with PM. Imaging at the time showed a lingular mass. He was treated with antifungal for 1 year until complete radiological resolution. Surgical intervention was considered but no further follow‐up action was taken. In 2020, he presented with fever and haemoptysis. Imaging again showed a lingular mass, which was confirmed to be PM by bronchoscopic lung biopsy. This case highlights the importance of secondary antifungal prophylaxis for PM if permanent reversal of immunosuppression is not possible.