Open AccessA rare case of thymoma with CA 19‐9 production
Author(s) -
Ohashi Takuya,
Kawago Mitsumasa,
Hirai Yoshimitsu,
Kiyoi Megumi,
Miyasaka Miwako,
Yata Yumi,
Kawaji Mari,
Fusamoto Aya,
Iguchi Hideto,
Nakanishi Hitomi,
Nishimura Yoshiharu
Publication year - 2021
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.844
Subject(s) - thymoma , thymectomy , medicine , myasthenia gravis , mediastinal tumor , immunohistochemistry , computed tomography , positron emission tomography , stage (stratigraphy) , rare disease , pathology , radiology , gastroenterology , disease , mediastinum , biology , paleontology
A 72‐year‐old man was diagnosed as having myasthenia gravis (MG). He underwent computed tomography which revealed an anterior mediastinal tumour. Laboratory examination revealed elevated levels (106.3 U/ml) of carbohydrate antigen (CA) 19‐9 in serum. However, no malignant disease was detected on fluorodeoxyglucose‐positron emission tomography. A diagnosis of thymoma associated with MG was considered and an extended thymectomy was performed. Histopathologically, thymoma was categorized as stage I based on the Masaoka classification, and as type AB according to the World Health Organization classification. Immunohistochemistry was positive for CA 19‐9. The serum levels returned to the normal range post‐operatively (16.7 U/ml). Herein, we report an extremely rare case of thymoma with raised levels of CA 19‐9.