Open AccessA case of epithelioid cell granulomas arising at the margin of lung resection, with high accumulation on 18F ‐fluorodeoxyglucose‐positron emission tomography
Author(s) -
Yokotsuka Shinnosuke,
Uematsu Shugo,
Okada Momoka,
Takamiya Shinnosuke,
Ohashi Shinichi,
Tanaka Yoko,
Suzuki Kosuke,
Kitami Akihiko,
Nemoto Tetsuo
Publication year - 2021
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.830
Subject(s) - medicine , atelectasis , positron emission tomography , caseous necrosis , fluorodeoxyglucose , radiology , granuloma , standardized uptake value , lung , pathological , positron emission , nuclear medicine , pathology , biopsy
It is important to distinguish tumour recurrence from other conditions that could show high accumulation on 18F‐fluorodeoxyglucose‐positron emission tomography (FDG‐PET). We describe the case of a 78‐year‐old woman who underwent partial resection of the left lower lung lobe for carcinoid treatment 20 years previously. Five years earlier, chest radiography revealed an abnormal shadow, and chest computed tomography (CT) showed partial atelectasis in the left S8. Periodical CT showed that the atelectasis had developed into a mass. The patient was referred to our hospital. A mass of 45 mm diameter was detected on CT and it had a maximum standardized uptake value of 8.91 on FDG‐PET. We suspected recurrence and performed surgery. Pathological examination revealed epithelioid cell granuloma (maximum diameter, 25 mm) with necrosis. Tissue culture showed no evidence of Mycobacterium tuberculosis . However, serum anti‐MAC antibody level was elevated, suggesting epithelioid cell granuloma caused by non‐tuberculous Mycobacterium infection.