Open AccessCatamenial haemoptysis in females with cystic fibrosis: a case series with review of management strategies
Author(s) -
Bozkanat Kubra M.,
West Natalie E.,
Ladores Sigrid,
Montemayor Kristina,
Tupayachi Ortiz Maria Gabriela,
Christianson Mindy,
Jain Raksha
Publication year - 2021
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.755
Subject(s) - medicine , cystic fibrosis , embolization , cystic fibrosis transmembrane conductance regulator , bronchial artery , fibrosis , hormone , endometriosis , surgery
Catamenial haemoptysis, the expectoration of blood during menses, has not been extensively reported in the cystic fibrosis (CF) literature. We describe four cases (age range: 25–34 years) of catamenial haemoptysis across four CF centres in the United States. These cases may represent thoracic endometriosis versus hormonal fluctuations in airway inflammation or infection resulting in bronchial artery bleeding. We identify common and nuanced management strategies including use of pro‐coagulants, hormone contraceptives, anti‐inflammatories, bronchial artery embolization, and use of the newer cystic fibrosis transmembrane conductance regulator (CFTR) modulators.