Open AccessLarge cell carcinoma of the lung presenting as diffuse pulmonary infiltrates with haemoptysis
Author(s) -
Seong Gil Myeong,
Hyun Chang Lim,
Lee Jonggeun,
Kim Changhwan
Publication year - 2020
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.632
Subject(s) - medicine , pathology , lung cancer , differential diagnosis , pathogenesis , lung , carcinoma , necrosis , basal cell , cell , large cell , cancer , adenocarcinoma , biology , genetics
Due to rapid advances in our understanding of the molecular pathogenesis of non‐small cell lung cancer (NSCLC), the 2015 World Health Organization (WHO) classification has defined large cell carcinoma (LCC) as a subtype that is lacking glandular or squamous cells, and any neuroendocrine differentiation. Accordingly, LCC is one of the rarest subtypes of NSCLC. LCC usually presents as a large peripheral tumour with prominent necrosis and its specific characteristics are not well known. Here, we report a case of LCC identified during differential diagnosis of diffuse alveolar haemorrhage in a patient with haemoptysis.