Open AccessSevere acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage
Author(s) -
Crisafulli Ernesto,
Burgazzi Barbara,
Majori Maria,
Serra Walter,
Chetta Alfredo
Publication year - 2020
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.531
Subject(s) - medicine , diffuse alveolar hemorrhage , acute respiratory failure , clopidogrel , respiratory failure , context (archaeology) , warfarin , continuous positive airway pressure , ards , airway , discontinuation , acute coronary syndrome , respiratory system , intensive care medicine , anesthesia , lung , myocardial infarction , mechanical ventilation , atrial fibrillation , paleontology , obstructive sleep apnea , biology
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was related to the administration of clopidogrel and warfarin, both implicated in the context of a polycythaemia. He developed a severe acute respiratory failure treated with a ventilatory support by means of a continuous positive airway pressure (C‐PAP) therapy. An improvement of patient's clinical conditions was observed only after clopidogrel and warfarin discontinuation.