Open AccessAlveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
Author(s) -
Hayakawa Takamitsu,
Tajima Shogo,
Takanashi Yusuke,
Takahashi Tsuyoshi,
Neyatani Hiroshi,
Funai Kazuhito
Publication year - 2016
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.175
Subject(s) - parietal pleura , medicine , mesothelioma , pathology , parenchyma , pleural effusion , sarcomatoid carcinoma , lung , biopsy , pneumonectomy , radiology , lung cancer , immunohistochemistry
A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63‐year‐old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia confirmed the diagnosis of sarcomatoid malignant pleural mesothelioma. The patient underwent left extra‐pleural pneumonectomy. Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar‐filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar‐filling growth pattern, despite having not been thoroughly categorized in the World Health Organization ( WHO ) classification.