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Tool command language automation of the modular ion cyclotron data acquisition system (MIDAS) for data‐dependent tandem Fourier transform ion cyclotron resonance mass spectrometry
Author(s) -
Freitas Michael A.,
King Eric,
Shi Stone D.H.
Publication year - 2003
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.922
Subject(s) - fourier transform ion cyclotron resonance , data acquisition , modular design , chemistry , automation , waveform , mass spectrometry , cyclotron , ion cyclotron resonance , top down proteomics , computer hardware , computer science , ion , tandem mass spectrometry , selected reaction monitoring , engineering , operating system , telecommunications , mechanical engineering , radar , organic chemistry , chromatography
Abstract This manuscript describes the addition of data‐dependent automation to the modular ion cyclotron resonance data acquisition system (MIDAS). The automation is made possible by developments and incorporation of a tool command language (Tcl) interpreter for automated acquisition. To accomplish the automation, real‐time generation of excitation waveforms and scriptable data post‐processing has been implemented into the MIDAS source code. In addition a new excitation event has also been added to allow for run‐time generation of a single notch stored waveform inverse Fourier transform (SWIFT) excitation event. Examples of these new features and discussion of their enhancement to the existing data station are presented. Copyright © 2003 John Wiley & Sons, Ltd.