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Double resonance ejection using novel radiofrequency phase tracking circuitry in a miniaturized planar linear ion trap mass spectrometer
Author(s) -
Decker Trevor K.,
Zheng Yajun,
McClellan Joshua S.,
Ruben Aaron J.,
Lammert Stephen A.,
Austin Daniel E.,
Hawkins Aaron R.
Publication year - 2018
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.8267
Subject(s) - chemistry , miniaturization , resonance (particle physics) , ion trap , quadrupole ion trap , planar , ion , mass spectrometry , tracking (education) , signal (programming language) , nuclear magnetic resonance , analytical chemistry (journal) , atomic physics , physics , materials science , nanotechnology , psychology , pedagogy , computer graphics (images) , organic chemistry , chromatography , computer science , programming language
Rationale Ion trap mass spectrometers are attractive due to their inherent sensitivity and specificity. Miniaturization increases trap portability for in situ mass analysis by relaxing vacuum and voltage requirements but decreases the trapping volume. To overcome signal/resolution loss from miniaturization, double resonance ejection using phase tracking circuitry was investigated. Methods Phase tracking circuitry was developed to induce double resonance ejection in a planar linear ion trap using the β 2/3 hexapole resonance line. Results Double resonance was observed using phase tracking circuitry. Resolution of 0.5 m/z units and improved signal‐to‐noise ratio (SNR) compared with AC resonant ejection were achieved. Conclusions The phase tracking circuitry proved effective despite deviations from a true phase locked condition. Double resonance ejection is a means to increase signal intensity in a miniaturized planar ion trap.