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On the detailed mechanisms of collision‐induced dissociation experiments performed by electrospray ion trap
Author(s) -
Catinella Silvia,
Pelizzi Nicola,
Barboso Silvia,
Favretto Donata,
Seraglia Roberta,
Traldi Pietro
Publication year - 2002
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.801
Subject(s) - chemistry , ion trap , quadrupole ion trap , ion , electrospray , trap (plumbing) , dissociation (chemistry) , electrospray ionization , mass spectrometry , collision induced dissociation , ion source , atomic physics , analytical chemistry (journal) , quadrupole , ionization , tandem mass spectrometry , chromatography , organic chemistry , physics , environmental engineering , engineering
The product ion spectra obtained by electrospray ionization (ESI) ion trap instruments exhibit a higher number of fragment ions than those achieved by other ion‐trap‐based systems, indicating the presence of more effective energy deposition mechanisms. This behavior can be attributed to several different reasons, among which different initial internal energy of the precursor ions, pre‐activation due to collisions taking place outside the trap, different target gas mixtures inside the trap, and different ion trap geometry were considered. Data obtained from experiments using a triple quadrupole instrument, CI‐ion trap, and ESI‐ion trap have been compared. The results so achieved seem to indicate that the presence inside the trap of neutral molecules of the solvent employed for the ESI process have a relevant role, promoting high energy deposition in the colliding ions. Copyright © 2002 John Wiley & Sons, Ltd.