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Analysis of peptides using partial (no discharge) atmospheric pressure chemical ionization conditions with ion trap mass spectrometry
Author(s) -
Cristoni Simone,
Bernardi Luigi Rossi,
Biunno Ida,
Guidugli Federico
Publication year - 2002
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.772
Subject(s) - chemistry , atmospheric pressure chemical ionization , mass spectrometry , chromatography , ion trap , analytical chemistry (journal) , atmospheric pressure , chemical ionization , ionization , sample preparation in mass spectrometry , ion , electrospray ionization , organic chemistry , oceanography , geology
A novel approach, based on the use of atmospheric pressure chemical ionization ion trap mass spectrometry (APCI‐ITMS) conditions, but without using corona discharge, was used to analyze peptides. The proposed method was applied to three standard peptides (bombesin, trityrosine and tyrosine‐glycine‐glycine) as well as peptides obtained through enzymatic digestion of two standard proteins (horse cytochrome c and horse myoglobin). Copyright © 2002 John Wiley & Sons, Ltd.