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A novel chemical ionization reagent ion for organic analytes: the aquachloromanganese(II) cation [ClMn(H 2 O) + ]
Author(s) -
Gqamana Putuma P.,
Duan Penggao,
Fu Mingkun,
Gallardo Vanessa,
Kenttämaa Hilkka I.
Publication year - 2012
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.6187
Subject(s) - chemistry , fourier transform ion cyclotron resonance , reagent , mass spectrometry , chemical ionization , electron ionization , reactivity (psychology) , ether , ion , molecule , ionization , analytical chemistry (journal) , inorganic chemistry , organic chemistry , chromatography , medicine , alternative medicine , pathology
The reactivity of ClMn(H 2 O) + towards small organic compounds (L) was examined in a Fourier transform ion cyclotron resonance (FT‐ICR) mass spectrometer. The organic compounds studied are aliphatic and aromatic alcohols, aliphatic amines, ketones, an epoxide, an ether, a thiol and a phosphine. All the reactions lead to the formation of the ClMn(H 2 O)(L) + complex, which dissociates by loss of the H 2 O molecule. In general, the reactions were found to occur with high efficiencies (>85%), indicating them to be exothermic. Electron transfer was also observed between ClMn(H 2 O) + and compounds with low ionization energies (IE), to form the molecular ion (L +• ) of the analyte. Based on these observations, the IE of ClMn(H 2 O) + is approximated to be 8.1 ± 0.1 eV. Thus, the utility of ClMn(H 2 O) + as a chemical ionization reagent in mass spectrometry is expected to be limited to organic compounds with IEs greater than 8 eV. Copyright © 2012 John Wiley & Sons, Ltd.