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Electron ionization and electrospray ionization mass spectrometric study of a series of isomeric N ‐chloro(or bromo)benzyl‐substituted ( E )‐2′(3′‐ or 4′)‐hydroxy‐4‐stilbazole halides
Author(s) -
Prukała Dorota,
Prukała Wiesław,
Sikorski Marek
Publication year - 2010
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.4471
Subject(s) - chemistry , dehydrohalogenation , electron ionization , mass spectrum , fragmentation (computing) , halide , ionization , electrospray ionization , mass spectrometry , ion , chemical ionization , analytical chemistry (journal) , spectral line , organic chemistry , chromatography , physics , operating system , astronomy , computer science , catalysis
The electron ionization (EI) mass spectra and electrospray ionization (ESI) mass spectra of a series of isomeric N ‐chlorobenzyl‐ and N ‐bromobenzyl‐substituted ( E )‐2′(3′ or 4′)‐hydroxy‐4‐stilbazole chlorides and bromides (1–12) were recorded. The fragmentation pathways of all of the compounds and the characteristic fragment ions formed by EI‐MS were studied by means of B/E and B 2 / E constant linked‐scanning techniques. The formation of ions originating from preionization reactions, characteristic of quaternary halides under EI‐MS conditions, such as the elimination of chloro‐ or bromobenzyl halides, dehydrohalogenation or substitution reactions, is explained. As soft ionization methods cause no such degradation reactions, the ESI‐MS spectra of the studied compounds were also obtained for comparison. We thus demonstrated the applicability of EI‐MS even in cases when preionization takes place, as long as such secondary processes are properly accounted for. Copyright © 2010 John Wiley & Sons, Ltd.