Premium
Microsynthesis and gas chromatography/electron ionization mass spectrometric and tandem mass spectrometric analysis of cyclic alkylphosphonates for verification of the Chemical Weapons Convention
Author(s) -
Dubey Devendra K.,
Pardasani Deepak,
Kanaujia Pankaj K.,
Tak Vijay,
Gupta Hemendra K.
Publication year - 2008
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.3644
Subject(s) - chemistry , fragmentation (computing) , electron ionization , chemical ionization , tandem , mass spectrum , gas chromatography , mass spectrometry , tandem mass spectrometry , polyatomic ion , gas chromatography/tandem mass spectrometry , alkene , ion , chromatography , analytical chemistry (journal) , ionization , organic chemistry , catalysis , materials science , computer science , composite material , operating system
We describe the microsynthesis and gas chromatography/mass spectrometric (GC/MS) analysis of cyclic alkylphosphonates (CAPs), which are included in schedule 2B4 chemicals in the Chemical Weapons Convention (CWC). The reported microsynthesis is efficient in comparison with traditional synthesis. GC/MS and GC/tandem mass spectrometric (MS/MS) analysis of a variety of CAPs revealed that their fragmentations were dominated by α ‐cleavages, alkene eliminations and hydrogen rearrangements. Based on the obtained mass spectra and precursor and product ion analysis of five‐, six‐ and seven‐membered cyclic alkylphosphonates, the proposed fragmentation routes rationalize most of the characteristic ions. Copyright © 2008 John Wiley & Sons, Ltd.