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Isotope correction of mass spectrometry profiles
Author(s) -
Eibl Günther,
Bernardo Katussevani,
Koal Therese,
Ramsay Steven L.,
Weinberger Klaus M.,
Graber Armin
Publication year - 2008
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.3591
Subject(s) - chemistry , mass spectrometry , isotope , analytical chemistry (journal) , chromatography , nuclear physics , physics
Isotope correction of a profile is an important step in the analysis of mass spectrometry derived data. The problem is mathematically formulated as a system of linear equations which is general enough to include previous correction methods. For the solution of these equations when applied to the whole profile an efficient algorithm is developed. In experimental tests the resulting algorithm corrected the profile fast and successfully. Copyright © 2008 John Wiley & Sons, Ltd.