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Electron ionisation and electrospray ionisation mass spectrometric study of a series of isomeric methyl‐, dimethyl‐ and trimethylalloxazines
Author(s) -
Prukała Dorota,
Prukała Wiesław,
Koczorowski Ryszard,
Khmelinskii Igor V.,
Sikorska Ewa,
Sikorski Marek
Publication year - 2008
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.3378
Subject(s) - chemistry , fragmentation (computing) , electron ionization , mass spectrum , electrospray , analytical chemistry (journal) , mass spectrometry , ionization , ion , electrospray ionization , benzene , spectral line , organic chemistry , chromatography , physics , astronomy , computer science , operating system
Electron ionisation (EI) mass spectra and electrospray ionisation (ESI) mass spectra at different cone voltages of a series of isomeric methyl‐ and dimethylalloxazines are discussed, and compared with those of lumichrome, and 1‐ and 3‐methyllumichrome. Examination of ESI mass spectra taken at a higher cone voltage and the use of isotope‐labelled methanol allow us to discuss the fragmentation pathways of [M+H] + and [M–H] − ions. The fragmentation pathways of all of the compounds and the characteristic fragment ions formed in EI‐MS are compared with published data. The influence of methyl and dimethyl substituents in the benzene ring on the fragmentation pathways leading to the loss of 43 and 45 Da upon both electron and electrospray ionisation is described. Copyright © 2008 John Wiley & Sons, Ltd.