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Combinatorial synthesis, reversed‐phase and normal‐phase high‐performance liquid chromatography elution data and liquid chromatography/positive atmospheric pressure chemical ionization tandem mass spectra of methoxylated and glycosylated resveratrol analogues
Author(s) -
Jerkovic Vesna,
Nguyen Fanny,
Nizet Sabrina,
Collin Sonia
Publication year - 2007
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.3116
Subject(s) - chemistry , atmospheric pressure chemical ionization , chromatography , liquid chromatography–mass spectrometry , chemical ionization , tandem , tandem mass spectrometry , elution , mass spectrometry , high performance liquid chromatography , analytical chemistry (journal) , atmospheric pressure , mass spectrum , unavailability , ionization , organic chemistry , ion , materials science , composite material , engineering , reliability engineering , oceanography , geology
Analyses of methoxylated and glycosylated stilbenes remain scarce in the literature because of the commercial unavailability of these compounds. Here a library of 22 compounds was synthesized by combinatorial chemistry. Their elution profiles were compared on three different columns (C18, C8, and silica) with those of seven commercial resveratrol analogues and two viniferins. The spectra recorded by liquid chromatography/positive atmospheric pressure chemical ionization tandem mass spectrometry (LC‐APCI(+)‐MS/MS) are discussed and recommendations made for easier identification of new stilbenes. Copyright © 2007 John Wiley & Sons, Ltd.