Do  b ‐ions occur from vibrational excitation upon H‐desorption in electron capture dissociation? | Zendy

Haselmann Kim F. | Zendy; Schmidt Marcel | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Do b ‐ions occur from vibrational excitation upon H‐desorption in electron capture dissociation?

Author(s) -

Haselmann Kim F.,

Schmidt Marcel

Publication year - 2007

Publication title -

rapid communications in mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.528

H-Index - 136

eISSN - 1097-0231

pISSN - 0951-4198

DOI - 10.1002/rcm.2932

Subject(s) - chemistry , dissociation (chemistry) , ion , fragmentation (computing) , collision induced dissociation , excitation , electron ionization , hydrogen , electron capture dissociation , ammonia , desorption , electron capture , spectral line , photochemistry , analytical chemistry (journal) , mass spectrometry , tandem mass spectrometry , ionization , fourier transform ion cyclotron resonance , adsorption , organic chemistry , chromatography , physics , engineering , operating system , astronomy , computer science , electrical engineering

Electron capture dissociation (ECD) has recently been shown in some cases to produce abundant N‐terminal b ‐ion peptide fragments. These product ions are usually only observed when activation occurs via vibrational excitation as in collision‐induced dissociation (CID). Here, we show that occurrence of b ‐ions in the ECD spectra of synthetic peptides are correlated with low gas‐phase basicity and that the observed b ‐ion fragments are N‐terminal products. Furthermore, all ECD spectra containing b ‐ions also had abundant losses of hydrogen and ammonia from the charge‐reduced species. Copyright © 2007 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research