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Electrospray ionization mass spectrometry fingerprinting of perfumes: rapid classification and counterfeit detection
Author(s) -
Marques Lygia de Azevedo,
Catharino Rodrigo Ramos,
Bruns Roy E.,
Eberlin Marcos N.
Publication year - 2006
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2779
Subject(s) - chemistry , counterfeit , electrospray ionization , chromatography , mass spectrometry , electrospray , extractive electrospray ionization , analytical chemistry (journal) , sample preparation in mass spectrometry , political science , law
A fast procedure to classify perfumes and identify counterfeit samples is described. Dilution of a few µL of the sample in a 1:1 methanol/water solution is followed by detection of its major polar components via direct infusion electrospray ionization mass spectrometry (ESI‐MS) in the positive ion mode. As proof‐of‐principle cases, three famous brands of perfumes were used. The ESI(+)‐MS fingerprints of authentic samples were very characteristic, showing distinctive sets of polar markers for each sample. Principal component analysis (PCA) placed samples of the three perfume brands in well‐defined groups. Counterfeit samples were also clearly detected owing to contrasting ESI‐MS fingerprints, with PCA placing these samples far away from the authentic samples. Copyright © 2006 John Wiley & Sons, Ltd.