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Metal ion adducts in the structural analysis of ginsenosides by electrospray ionization with multi‐stage mass spectrometry
Author(s) -
Cui Meng,
Song Fengrui,
Liu Zhiqiang,
Liu Shuying
Publication year - 2001
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.264
Subject(s) - chemistry , glycosidic bond , adduct , mass spectrometry , electrospray ionization , fast atom bombardment , dissociation (chemistry) , molecule , electrospray , tandem mass spectrometry , collision induced dissociation , protein mass spectrometry , chromatography , analytical chemistry (journal) , organic chemistry , enzyme
The effect of metal (Li + , Na + , K + , Ag + ) cationization on collision‐induced dissociation of ginsenosides was investigated by electrospray ionization mass spectrometry combined with multi‐stage mass spectrometry (ESI‐MS n ). The fragments of sodiated and lithiated molecules give valuable structural information regarding the nature of the aglycone and the sequence and linkage information of sugar moieties. However, the number and relative abundances of fragment ions from lithiated ginsenosides are significantly greater than for the sodiated species. The K + adducts undergo glycosidic cleavages and very limited cross‐ring reactions. The silver ion adducts fragment mainly through glycosidic cleavages. Copyright © 2001 John Wiley & Sons, Ltd.