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A deflection system to reduce the interference from post‐source decay product ions in photodissociation tandem time‐of‐flight mass spectrometry
Author(s) -
Yoon So Hee,
Moon Jeong Hee,
Choi Kyung Mi,
Kim Myung Soo
Publication year - 2006
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2584
Subject(s) - chemistry , tandem , photodissociation , ion , mass spectrometry , tandem mass spectrometry , mass spectrum , ionization , analytical chemistry (journal) , deflection (physics) , ion source , time of flight , optics , photochemistry , chromatography , physics , aerospace engineering , organic chemistry , engineering
A deflection system consisting of four deflectors was designed and used to reduce the interference from post‐source decay (PSD) product ions in photodissociation (PD) tandem time‐of‐flight (TOF) mass spectrometry. For simple protonated peptides generated by matrix‐assisted laser desorption/ionization, the presence of PSD product ions at the laser irradiation spot was found to noticeably alter the minor peaks in the PD spectra even though the major ones were hardly affected. Other benefits from the use of the deflection system such as the improvement in the resolving power in PSD tandem mass spectra are discussed. Copyright © 2006 John Wiley & Sons, Ltd.