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Comparison of the fragmentation pattern induced by collisions, laser excitation and electron capture. Influence of the initial excitation
Author(s) -
Antoine R.,
Broyer M.,
ChamotRooke J.,
Dedonder C.,
Desfrançois C.,
Dugourd P.,
Grégoire G.,
Jouvet C.,
Onidas D.,
Poulain P.,
Tabarin T.,
van der Rest G.
Publication year - 2006
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2489
Subject(s) - chemistry , excitation , fragmentation (computing) , dissociation (chemistry) , pentapeptide repeat , atomic physics , electron ionization , electron , electron excitation , laser , electron capture dissociation , electron capture , collision induced dissociation , monte carlo method , mass spectrometry , molecular physics , ionization , tandem mass spectrometry , ion , peptide , physics , nuclear physics , optics , biochemistry , statistics , mathematics , organic chemistry , chromatography , quantum mechanics , computer science , operating system
Abstract Collision‐induced dissociation, laser‐induced dissociation and electron‐capture dissociation are compared on a singly and doubly protonated pentapeptide. The dissociation spectrum depends on the excitation mechanism and on the charge state of the peptide. The comparison of these results with the conformations obtained from Monte Carlo simulations suggests that the de‐excitation mechanism following a laser or an electron‐capture excitation is related to the initial geometry of the peptide. Copyright © 2006 John Wiley & Sons, Ltd.