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Electrospray ionization mass spectrometric studies of some imidazole amidoximes and nitrolic acids and their esters
Author(s) -
Oresmaa Larisa,
Aulaskari Paula,
Vainiotalo Pirjo
Publication year - 2006
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2418
Subject(s) - chemistry , imidazole , electrospray ionization , chromatography , electrospray , extractive electrospray ionization , mass spectrometry , organic chemistry , protein mass spectrometry
The fragmentations of the [M+H] + ions of imidazole amidoximes, and nitrolic acids and their esters, were studied by collision‐induced dissociation experiments and by determining the accurate masses of the product ions on an electrospray ionization Fourier transform ion cyclotron resonance mass spectrometer. The fragmentation pathways of the amidoximes varied with the substituent in the imidazole ring at position 1N, allowing two regioisomers to be distinguished. Nitrolic acids decompose in solution to nitrile oxides, and the studied nitrolic acid behaved in the same way in the gas phase. The esters decompose similarly to their parent compounds. Copyright © 2006 John Wiley & Sons, Ltd.