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Energy‐resolved in‐source collisionally induced dissociation for the evaluation of the relative stability of noncovalent complexes in the gas phase
Author(s) -
Lyapchenko Nataliya,
Schroeder Grzegorz
Publication year - 2005
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2212
Subject(s) - chemistry , dissociation (chemistry) , gas phase , collision induced dissociation , chemical physics , mass spectrometry , tandem mass spectrometry , chromatography
Energy‐resolved in‐source collisionally induced dissociation (CID) studies on the complexation of alkali metal cations by some crown ethers, nucleic acid bases, and amino acids have been performed. It has been shown that the cone voltage corresponding to the maximum ion abundance ( V c,Imax ) of the breakdown curve is characteristic of a given ion and not influenced by the cone desolvation process or the composition of the solution. Very good agreement of the V c,Imax value with the bond strength of the ion has been observed. Determination of the V c,Imax values for different ionic species is a useful, simple, and inexpensive way to obtain their relative stabilities in in‐source CID conditions. Copyright © 2005 John Wiley & Sons, Ltd.