Premium
Electrospray ionization mass spectrometric studies of nucleophilic carbenes derived from pyrazolium and indazolium carboxylates
Author(s) -
Schmidt Andreas,
Habeck Tobias,
Merkel Lars,
Mäkinen Marko,
Vainiotalo Pirjo
Publication year - 2005
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.2048
Subject(s) - chemistry , betaine , electrospray ionization , nucleophile , carboxylate , adduct , mass spectrometry , medicinal chemistry , ionization , stereochemistry , organic chemistry , chromatography , catalysis , ion
Pyrazolium‐3‐carboxylate and indazolium‐3‐carboxylate, which belong to the class of pseudo‐cross‐conjugated mesomeric betaines and which represent the electronically relevant partial structures of the betaine alkaloid Nigellicin, were examined by electrospray ionization mass spectrometry. These compounds decarboxylate to pyrazol‐3‐ylidene and indazol‐3‐ylidene. The formation of adducts of these new nucleophilic carbenes under the measurement conditions was examined. Copyright © 2005 John Wiley & Sons, Ltd.