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Electron ionization mass spectra of indolenines obtained using sector and ion trap mass spectrometers
Author(s) -
MoralesRíos Martha S.,
Velasco Luis,
PérezRojas Nadia A.,
JosephNathan Pedro
Publication year - 2005
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1930
Subject(s) - chemistry , fragmentation (computing) , electron ionization , ion trap , mass spectrometry , ion , mass spectrum , alkyl , ionization , analytical chemistry (journal) , alkoxy group , polyatomic ion , organic chemistry , chromatography , computer science , operating system
The electron impact (EI)‐induced fragmentations of 18 indolenines were studied using both double‐focusing and ion trap mass spectrometers. The compounds used in this study were synthesized to provide correlations of characteristic fragment ions with specific structural differences. In 2‐hydroxyindolenines the hydroxy group was involved in a major fragmentation process by interacting with the ester side chain to generate an α , β ‐unsaturated γ ‐lactone structure, with concomitant loss of the corresponding alcohol. In contrast, loss of an alkyl radical, derived solely from the 2‐alkoxy group, is a major primary decomposition process for 2‐alkoxyindolenines. EI‐MS analyses using sector and ion trap spectrometers resulted in similar fragmentation patterns. Copyright © 2005 John Wiley & Sons, Ltd.