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Ring contraction reactions of 2,3‐dihydro‐4 H ‐1,3‐oxazin‐4‐ones under electrospray ionization conditions
Author(s) -
Ma Yuan,
Liu Wei,
Chen Yi,
Zhao Yufen
Publication year - 2004
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1454
Subject(s) - chemistry , fragmentation (computing) , electrospray ionization , electrospray , mass spectrometry , ionization , stereochemistry , analytical chemistry (journal) , chromatography , organic chemistry , ion , computer science , operating system
The mass spectral behavior of 2,3‐dihydro‐4 H ‐1,3‐oxazin‐4‐ones has been investigated using electrospray ionization multi‐stage mass spectrometry (ESI‐MS n ). All compounds showed a predominant retro‐Diels‐Alder (RDA) fragmentation pathway, and a novel ring contraction reaction by loss of isocynates was also found. The fragmentation mechanisms proposed for 4 H ‐1,3‐oxazin‐4‐ones are supported by ESI‐MS/MS/MS spectra. Copyright © 2004 John Wiley & Sons, Ltd.