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Capillary electrochromatography/mass spectrometry: Principles and potential for application in the pharmaceutical industry
Author(s) -
Lane S. J.,
Boughtflower R.,
Paterson C.,
Underwood T.
Publication year - 1995
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290091312
Subject(s) - chemistry , capillary electrochromatography , mass spectrometry , electrochromatography , chromatography , biochemical engineering , capillary electrophoresis , engineering
Capillary electrochromatography (CEC) was coupled with electrospray (ESI) mass spectrometry and evaluated as an on‐line high resolution technique for the separation and characterization of some typical pharmaceutical compound mixtures. Dispersion effects were observed and are discussed in the context of an optimized CEC/MS interface.