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Error‐tolerant protein database searching using peptide product‐ion spectra
Author(s) -
Bonner Ron,
Shushan Bori
Publication year - 1995
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290091120
Subject(s) - chemistry , derivatization , peptide , database , matching (statistics) , product (mathematics) , database search engine , chromatography , combinatorial chemistry , computational biology , analytical chemistry (journal) , mass spectrometry , information retrieval , biochemistry , statistics , computer science , search engine , geometry , mathematics , biology
A method for matching proteins in databases with unknown samples using data derived from peptide production masses is described. The power of the method is due to the speed of analysis and to the ability to locate proteins in a database even when the experimental data show anomalies due to derivatization or post‐translational modification.